Elutriation. Washing. One system.
Our data set shows that samples prepared with the Korus™ elutriation protocol result in significantly higher T cell selection recovery and growth in comparison to samples prepared with the standard CS5+ wash protocol.
The Korus™ system is designed to get your manufacturing process off to the right start by providing you with a cleaner cell population.
Invetech offers a wide variety of custom solutions and ready-to-run systems for cell and gene therapy. This brochure gives a succinct overview of what you can expect from Invetech.
How does Korus™ separate cells?
The Korus™ uses the process of elutriation to separate cells. Learn more about the elutriation process.
Do you have data evaluation red blood cell (RBC) contamination in the Korus™ system?
Our data did look at RBC depletion, and you can view our complete dataset here.
What is the cell capacity of Korus™?
It depends upon cell type, but as an example each 50 mL chamber can accommodate 20 billion T cells.
Can I specify the output volume?
Yes, between 25 mL to 150 mL, independent of the input and wash volumes.
How low have you pushed the output volume range?
25 mL is the specified output lower limit, but in certain circumstances it is possible to go as low as 15 mL. For further information on how the Korus™ can be optimized to fit your protocol, please contact us here.
What’s the typical recovery?
Our complete dataset including typical recovery can be viewed here.
How long do these runs take?
Process time is somewhat dependent on input volume. For most applications, the process time will be under 60 minutes.
Are there specific buffers that should be used with the Korus™?
Invetech can assist with buffer and parameter selection. Please contact us here.
Can I optimize Korus™ to balance my purity and recovery requirements?
Yes, the Korus™ software enables optimization of your process parameters such as centrifuge speed, counterflow rate, counterflow ramp rate and elutriation volume so that you can balance your purity and recovery requirements.
Is the KorusTM a fully closed system? How do I attach my cells to the Korus™ system?
The Korus™ single-use set is fully closed, to which you can weld on your bag.
How difficult is it to put the single-use set on?
The single-use set takes fewer than five minutes for you to install. It comes neatly packaged in a tub, with aseptic connections already intact, and is designed to be intuitively connected to the Korus™.
What is the process for replacing Elutra?
We know that you may currently have an elutriation protocol that you are trying to replace. Schedule a demo to see how Korus™ can address your elutriation needs.
How much does it cost?
For pricing information, please contact us.